Some people are known to have trouble fighting infections because they make antibodies that deactivate their own interferon. On Thursday, a global consortium of researchers said such immune reactions to the protein could account for life-threatening Covid-19 pneumonia in at least 2.6% of women and 12.5% of men.
Interferons (IFNs, /ˌɪntərˈfɪərɒn/[1]) are a group of signaling proteins[2] made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.
This to me looks like a conflict in T-cell, which was the residual worry about this virus. The immune system is best with one infection at a time. If we get too many 'common viruses' then ultimately one of them cannot be serviced by the T-cell system, capacity is not there.
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